ON THE CHOICE OF ACOUSTIC SIGNAL PARAMETERS FOR VISUALIZATION OF BIOLOGICAL TISSUE STRUCTURE ON THE BASIS OF NONLINEAR INTERACTION OF ACOUSTIC WAVES
Keywords:
Non-linear parameter of an acoustic wave, ultrasound imaging, radiation parameters
Abstract
The paper considers the choice of optimal acoustic wave parameters for ultrasonic im-aging based on nonlinear effects of its interaction with biological tissues. The changes of the second harmonic pressure at different values of the frequency and pressure of the first har-monic are calculated. As a model, the medium consisting of the following biological tissues was considered: adipose tissue, muscle tissue, whole liver, blood, pathological tissue (fi-broids). For adipose and muscle tissues, the calculation of the change in the acoustic wave rupture distance at different parameters of the probing pulse of the main frequency was car-ried out. The calculation of the distance of the gap was conducted in order to determine the most optimal ratio of the initial characteristics of the ultrasonic wave and a second harmonic of an acoustic signal, allowing you to visualize the distribution of the acoustic nonlinearity parameter.
References
1. Rudenko O.V. Nelineynye volny: nekotorye biomeditsinskie prilozheniya [Nonlinear waves: some biomedical applications], Uspekhi fizicheskikh nauk [Success of physical Sciences], 2007, Vol. 177, No. 4, pp. 374-383.
2. Fizika vizualizatsii izobrazheniy v meditsine [Physics of image visualization in medicine]: in 2 vol. Vol. 2: transl. from the engl. ed. by S. Uebba. Moscow: Mir, 1991, 408 p.
3. Zarembo L.K., Timoshenko V.I. Nelineynaya akustika [Nonlinear acoustics]. Moscow: Izd-vo MGU, 1984, 104 p.
4. Xiufen Gong, Dong Zhang, Jiehui Liu, Huanlei Wang, Yongsheng Yan, and Xiaochen Xu. Study of acoustic nonlinearity parameter imaging methods in reflection mode for biological tissues. Acoustical Society of America, 2004, pp. 1819-1825.
5. Morris C.R., Wright W.E., Schlag R.D. The risk of developing breast cancer within the next 5, 10, or 20 years of a woman’s life», American Journal of Preventive Medicine, 2001, Vol. 20, Issue 3, pp. 214-218.
6. Fatemi M., Greenleaf J.F. Real-time assessment of the parameter of nonlinearity in tissue us-ing «nonlinear shadowing, Ultrasound in Med. & Biol., 1996, Vol. 22, No. 9, pp. 1215-1228.
7. Preobrazhenskiy S.V., Preobrazhenskiy V.L., Penro F., Bu Matar O. Diagnostika neodnorodnosti nelineynogo parametra akusticheskoy sredy s pomoshch'yu obrashcheniya volnovogo fronta ul'trazvuka [Diagnostics of non-uniformity of a nonlinear parameter of an acoustic medium using the reversal of the wave front of ultrasound], Akusticheskiy zhurnal [Akusticheskij zhurnal], 2008, Vol. 54, No. 1, pp. 20-25.
8. Varenikova A.Yu. Primenenie dinamicheskoy kharakteristiki nelineynogo vzaimodeystviya akusticheskikh voln dlya vizualizatsii biotkaney [ Application of dynamic characteristics of nonlinear interaction of acoustic waves for visualization of biotissues], Sb. materialov Dvadtsat' vtoroy Vserossiyskoy nauchnoy konferentsii studentov fizikov i molodykh uchenykh VNKSF-22 [Collection of materials of the Twenty-second all-Russian scientific conference of students of physics and young scientists VNKSF-22], 2016, pp. 330-331.
9. Burov V.A., Morozov S.A., Rumyantseva O.D., Sergeev S.N. Aktivnaya i passivnaya meditsinskaya akusticheskaya tomografiya sil'no neodnorodnykh sred [Active and passive medical acoustic tomography of highly heterogeneous media], Biomeditsinskie tekhnologii i radioelektronika [Biomedical technologies and Radioelectronics], 2002, No. 3, pp. 5-13.
10. Akimenko O.B., Zhardetskaya A.S., Chernov N.N. K voprosu o vizualizatsii vnutrennikh organov cheloveka na osnove nelineynostey biotkaney [On the issue of visualization of human internal organs based on non-linearity of biotissues], V Vserossiyskaya molodezhnaya shkola-seminar «Innovatsii i perspektivy meditsinskikh informatsionnykh sistem IPMIS-2016», 19-22 dekabrya 2016, g. Taganrog [V all-Russian youth school-seminar "Innovations and prospects of medical information systems IPMIS-2016", December 19-22, 2016, Taganrog], pp. 8-12.
11. Burov V.A., Shmelev A.A. Chislennoe i fizicheskoe modelirovanie protsessa tomografi-rovaniya na osnove akusticheskikh nelineynykh effektov tret'ego poryadka [Numerical and physical modeling of the tomography process based on acoustic nonlinear effects of the third order], Akusticheskiy zhurnal [Akusticheskij zhurnal], 2009, Vol. 55, No. 4-5, pp. 466-480.
12. Burov V.A., Zotov D.I., Rumyantseva O.D. Vosstanovlenie prostranstvennykh raspredeleniy skorosti zvuka i pogloshcheniya v fantomakh myagkikh biotkaney po eksperimental'nym dannym ul'trazvukovogo tomografirovaniya [Restoration of spatial distributions of sound ve-locity and absorption in soft biotissue phantoms based on experimental data of ultrasound to-mography], Akusticheskiy zhurnal [Akusticheskij zhurnal], 2015, Vol. 61, No. 2, pp. 254-273.
13. Greenleaf J.F. Computerized transmission tomography // Methods of experimental physics, Academic press. New York, 1981, Vol. 19.
14. Burov V.A., Gurenovich I.E., Rudenko O.V., Tabunov E.Ya. Rekonstruktsiya prostranstvennogo raspredeleniya parametra nelineynosti i skorosti zvuka v akusticheskoy nelineynoy tomografii [Reconstruction of the spatial distribution of the parameter of nonlinear-ity and speed of sound in acoustic nonlinear tomography], Akusticheskiy zhurnal [Akusticheskij zhurnal], 1994, Vol. 40, No. 6, pp. 922-929.
15. Zagray N.P. Nelineynye vzaimodeystviya v sloistykh i neodnorodnykh sredakh [Nonlinear interactions in layered and inhomogeneous media], ed. by akademika AEN RF V.I. Timoshen-ko. Taganrog: Izd-vo TRTU, 1998, 433 p.
16. Rudenko O.V., Soluyan S.N. Teoreticheskie osnovy nelineynoy akustiki [Theoretical founda-tions of nonlinear acoustics]. Moscow: Izd-vo Nauka, 1975.
17. Chernov N.N., Zagray N.P., Laguta M.V., Varenikova A.Yu. Appearance and Propagation of Higher Harmonics of Acoustic Signals in the Nonlinear Media, Journal of Physics: Confer-ence Series, 2018, Vol. 1015 (3), pp. 032-081.
18. Demin I.Yu., Pronchatov-Rubtsov N.V. Sovremennye akusticheskie metody issledovaniy v biologii i meditsine: uchebno-metodicheskiy material po programme povysheniya kvalifikatsii «KHranenie i obrabotka informatsii v biologicheskikh sistemakh» [Modern acoustic research methods in biology and medicine: educational and methodological material for the advanced training program "Storage and processing of information in biological systems"]. Nizhniy Novgorod, 2007, 121 p.
19. Novikov B.K., Rudenko O.V., Timoshenko V.I. Nelineynaya gidroakustika [Nonlinear hydroacoustics]. Leningrad: Sudostroenie, 1981, 264 p.
20. Burov V.A., Kryukov R.V., Rumyantseva O.D., Shmelev A.A. Problemy ispol'zovaniya nelineynykh kollinearnykh protsessov v akusticheskoy tomografii tret'ego poryadka [Problems of using nonlinear collinear processes in third-order acoustic tomography], Akusticheskiy zhurnal [Akusticheskij zhurnal], 2012, Vol. 58, No. 1, pp. 57-79.
2. Fizika vizualizatsii izobrazheniy v meditsine [Physics of image visualization in medicine]: in 2 vol. Vol. 2: transl. from the engl. ed. by S. Uebba. Moscow: Mir, 1991, 408 p.
3. Zarembo L.K., Timoshenko V.I. Nelineynaya akustika [Nonlinear acoustics]. Moscow: Izd-vo MGU, 1984, 104 p.
4. Xiufen Gong, Dong Zhang, Jiehui Liu, Huanlei Wang, Yongsheng Yan, and Xiaochen Xu. Study of acoustic nonlinearity parameter imaging methods in reflection mode for biological tissues. Acoustical Society of America, 2004, pp. 1819-1825.
5. Morris C.R., Wright W.E., Schlag R.D. The risk of developing breast cancer within the next 5, 10, or 20 years of a woman’s life», American Journal of Preventive Medicine, 2001, Vol. 20, Issue 3, pp. 214-218.
6. Fatemi M., Greenleaf J.F. Real-time assessment of the parameter of nonlinearity in tissue us-ing «nonlinear shadowing, Ultrasound in Med. & Biol., 1996, Vol. 22, No. 9, pp. 1215-1228.
7. Preobrazhenskiy S.V., Preobrazhenskiy V.L., Penro F., Bu Matar O. Diagnostika neodnorodnosti nelineynogo parametra akusticheskoy sredy s pomoshch'yu obrashcheniya volnovogo fronta ul'trazvuka [Diagnostics of non-uniformity of a nonlinear parameter of an acoustic medium using the reversal of the wave front of ultrasound], Akusticheskiy zhurnal [Akusticheskij zhurnal], 2008, Vol. 54, No. 1, pp. 20-25.
8. Varenikova A.Yu. Primenenie dinamicheskoy kharakteristiki nelineynogo vzaimodeystviya akusticheskikh voln dlya vizualizatsii biotkaney [ Application of dynamic characteristics of nonlinear interaction of acoustic waves for visualization of biotissues], Sb. materialov Dvadtsat' vtoroy Vserossiyskoy nauchnoy konferentsii studentov fizikov i molodykh uchenykh VNKSF-22 [Collection of materials of the Twenty-second all-Russian scientific conference of students of physics and young scientists VNKSF-22], 2016, pp. 330-331.
9. Burov V.A., Morozov S.A., Rumyantseva O.D., Sergeev S.N. Aktivnaya i passivnaya meditsinskaya akusticheskaya tomografiya sil'no neodnorodnykh sred [Active and passive medical acoustic tomography of highly heterogeneous media], Biomeditsinskie tekhnologii i radioelektronika [Biomedical technologies and Radioelectronics], 2002, No. 3, pp. 5-13.
10. Akimenko O.B., Zhardetskaya A.S., Chernov N.N. K voprosu o vizualizatsii vnutrennikh organov cheloveka na osnove nelineynostey biotkaney [On the issue of visualization of human internal organs based on non-linearity of biotissues], V Vserossiyskaya molodezhnaya shkola-seminar «Innovatsii i perspektivy meditsinskikh informatsionnykh sistem IPMIS-2016», 19-22 dekabrya 2016, g. Taganrog [V all-Russian youth school-seminar "Innovations and prospects of medical information systems IPMIS-2016", December 19-22, 2016, Taganrog], pp. 8-12.
11. Burov V.A., Shmelev A.A. Chislennoe i fizicheskoe modelirovanie protsessa tomografi-rovaniya na osnove akusticheskikh nelineynykh effektov tret'ego poryadka [Numerical and physical modeling of the tomography process based on acoustic nonlinear effects of the third order], Akusticheskiy zhurnal [Akusticheskij zhurnal], 2009, Vol. 55, No. 4-5, pp. 466-480.
12. Burov V.A., Zotov D.I., Rumyantseva O.D. Vosstanovlenie prostranstvennykh raspredeleniy skorosti zvuka i pogloshcheniya v fantomakh myagkikh biotkaney po eksperimental'nym dannym ul'trazvukovogo tomografirovaniya [Restoration of spatial distributions of sound ve-locity and absorption in soft biotissue phantoms based on experimental data of ultrasound to-mography], Akusticheskiy zhurnal [Akusticheskij zhurnal], 2015, Vol. 61, No. 2, pp. 254-273.
13. Greenleaf J.F. Computerized transmission tomography // Methods of experimental physics, Academic press. New York, 1981, Vol. 19.
14. Burov V.A., Gurenovich I.E., Rudenko O.V., Tabunov E.Ya. Rekonstruktsiya prostranstvennogo raspredeleniya parametra nelineynosti i skorosti zvuka v akusticheskoy nelineynoy tomografii [Reconstruction of the spatial distribution of the parameter of nonlinear-ity and speed of sound in acoustic nonlinear tomography], Akusticheskiy zhurnal [Akusticheskij zhurnal], 1994, Vol. 40, No. 6, pp. 922-929.
15. Zagray N.P. Nelineynye vzaimodeystviya v sloistykh i neodnorodnykh sredakh [Nonlinear interactions in layered and inhomogeneous media], ed. by akademika AEN RF V.I. Timoshen-ko. Taganrog: Izd-vo TRTU, 1998, 433 p.
16. Rudenko O.V., Soluyan S.N. Teoreticheskie osnovy nelineynoy akustiki [Theoretical founda-tions of nonlinear acoustics]. Moscow: Izd-vo Nauka, 1975.
17. Chernov N.N., Zagray N.P., Laguta M.V., Varenikova A.Yu. Appearance and Propagation of Higher Harmonics of Acoustic Signals in the Nonlinear Media, Journal of Physics: Confer-ence Series, 2018, Vol. 1015 (3), pp. 032-081.
18. Demin I.Yu., Pronchatov-Rubtsov N.V. Sovremennye akusticheskie metody issledovaniy v biologii i meditsine: uchebno-metodicheskiy material po programme povysheniya kvalifikatsii «KHranenie i obrabotka informatsii v biologicheskikh sistemakh» [Modern acoustic research methods in biology and medicine: educational and methodological material for the advanced training program "Storage and processing of information in biological systems"]. Nizhniy Novgorod, 2007, 121 p.
19. Novikov B.K., Rudenko O.V., Timoshenko V.I. Nelineynaya gidroakustika [Nonlinear hydroacoustics]. Leningrad: Sudostroenie, 1981, 264 p.
20. Burov V.A., Kryukov R.V., Rumyantseva O.D., Shmelev A.A. Problemy ispol'zovaniya nelineynykh kollinearnykh protsessov v akusticheskoy tomografii tret'ego poryadka [Problems of using nonlinear collinear processes in third-order acoustic tomography], Akusticheskiy zhurnal [Akusticheskij zhurnal], 2012, Vol. 58, No. 1, pp. 57-79.
Published
2020-06-29
Issue
Section
SECTION I. METHODS AND TOOLS FOR ENVIRONMENTAL MONITORING
